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Mitochondria-mediated apoptosis is also called the intrinsic pathway and occurs in response to a wide range of death stimuli, and is characterized by cascade reactions including mitochondrial outer membrane permeabilization (MOMP), release of cytochrome c into the cytoplasm to activate caspase-9 and subsequent caspase-3 [5, 6]

In contrast, wounds treated with zinc oxide and control wounds remained clean and free of exudate throughout the study, with granulation tissue formation being less remarkable in these groups on days 7 and 8

Metabolic monitoring: Because tesamorelin strongly stimulates GH, IGF-1 should be monitored periodically and blood glucose watched in patients with diabetes [6]

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